Rutin Is a Low Micromolar Inhibitor of SARS-CoV-2 Main Protease 3CLpro: Implications for Drug Design of Quercetin Analogs

The pandemic, due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has stimulated the search for antivirals to tackle COVID-19 infection. Molecules with known pharmacokinetics and already approved for human use have been demonstrated or predicted to be suitable to be used either dire...

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Detalles Bibliográficos
Autores principales: Rizzuti, Bruno, Grande, Fedora, Conforti, Filomena, Jimenez-Alesanco, Ana, Ceballos-Laita, Laura, Ortega-Alarcon, David, Vega, Sonia, Reyburn, Hugh T., Abian, Olga, Velazquez-Campoy, Adrian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066963/
https://www.ncbi.nlm.nih.gov/pubmed/33918402
http://dx.doi.org/10.3390/biomedicines9040375

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066963/
https://www.ncbi.nlm.nih.gov/pubmed/33918402
http://dx.doi.org/10.3390/biomedicines9040375

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