Impact of Mammalian Two-Pore Channel Inhibitors on Long-Distance Electrical Signals in the Characean Macroalga Nitellopsis obtusa and the Early Terrestrial Liverwort Marchantia polymorpha

Inhibitors of human two-pore channels (TPC1 and TPC2), i.e., verapamil, tetrandrine, and NED-19, are promising medicines used in treatment of serious diseases. In the present study, the impact of these substances on action potentials (APs) and vacuolar channel activity was examined in the aquatic ch...

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Detalles Bibliográficos
Autores principales: Koselski, Mateusz, Pupkis, Vilmantas, Hashimoto, Kenji, Lapeikaite, Indre, Hanaka, Agnieszka, Wasko, Piotr, Plukaite, Egle, Kuchitsu, Kazuyuki, Kisnieriene, Vilma, Trebacz, Kazimierz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067100/
https://www.ncbi.nlm.nih.gov/pubmed/33805421
http://dx.doi.org/10.3390/plants10040647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067100/
https://www.ncbi.nlm.nih.gov/pubmed/33805421
http://dx.doi.org/10.3390/plants10040647

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