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Targeting the ATP Synthase in Staphylococcus aureus Small Colony Variants, Streptococcus pyogenes and Pathogenic Fungi

The ATP synthase has been validated as a druggable target with the approval of the ATP synthase inhibitor, bedaquiline, for treatment of drug-resistant Mycobacterium tuberculosis, a bacterial species in which the ATP synthase is essential for viability. Gene inactivation studies have also shown that...

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Detalles Bibliográficos
Autores principales: Vestergaard, Martin, Roshanak, Sahar, Ingmer, Hanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067178/
https://www.ncbi.nlm.nih.gov/pubmed/33918382
http://dx.doi.org/10.3390/antibiotics10040376