Priming of the cGAS-STING-TBK1 Pathway Enhances LPS-Induced Release of Type I Interferons

Cytoplasmic nucleic acids sensing through cGAS-STING-TBK1 pathway is crucial for the production of antiviral interferons (IFNs). IFN production can also be induced by lipopolysaccharide (LPS) stimulation through Toll-like receptor 4 (TLR4) in appropriate conditions. Of note, both IFN production and...

Descripción completa

Detalles Bibliográficos
Autores principales: Tesser, Alessandra, Piperno, Giulia Maria, Pin, Alessia, Piscianz, Elisa, Boz, Valentina, Benvenuti, Federica, Tommasini, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067196/
https://www.ncbi.nlm.nih.gov/pubmed/33916318
http://dx.doi.org/10.3390/cells10040785

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067196/
https://www.ncbi.nlm.nih.gov/pubmed/33916318
http://dx.doi.org/10.3390/cells10040785

Ejemplares similares