The Bacteriostatic Activity of 2-Phenylethanol Derivatives Correlates with Membrane Binding Affinity

The hydrophobic tails of aliphatic primary alcohols do insert into the hydrophobic core of a lipid bilayer. Thereby, they disrupt hydrophobic interactions between the lipid molecules, resulting in a decreased lipid order, i.e., an increased membrane fluidity. While aromatic alcohols, such as 2-pheny...

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Detalles Bibliográficos
Autores principales: Kleinwächter, Isabel S., Pannwitt, Stefanie, Centi, Alessia, Hellmann, Nadja, Thines, Eckhard, Bereau, Tristan, Schneider, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067230/
https://www.ncbi.nlm.nih.gov/pubmed/33807437
http://dx.doi.org/10.3390/membranes11040254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067230/
https://www.ncbi.nlm.nih.gov/pubmed/33807437
http://dx.doi.org/10.3390/membranes11040254

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