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The Bacteriostatic Activity of 2-Phenylethanol Derivatives Correlates with Membrane Binding Affinity
The hydrophobic tails of aliphatic primary alcohols do insert into the hydrophobic core of a lipid bilayer. Thereby, they disrupt hydrophobic interactions between the lipid molecules, resulting in a decreased lipid order, i.e., an increased membrane fluidity. While aromatic alcohols, such as 2-pheny...
Autores principales: | Kleinwächter, Isabel S., Pannwitt, Stefanie, Centi, Alessia, Hellmann, Nadja, Thines, Eckhard, Bereau, Tristan, Schneider, Dirk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067230/ https://www.ncbi.nlm.nih.gov/pubmed/33807437 http://dx.doi.org/10.3390/membranes11040254 |
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