Glioma stem cells invasive phenotype at optimal stiffness is driven by MGAT5 dependent mechanosensing

BACKGROUND: Glioblastomas stem-like cells (GSCs) by invading the brain parenchyma, remains after resection and radiotherapy and the tumoral microenvironment become stiffer. GSC invasion is reported as stiffness sensitive and associated with altered N-glycosylation pattern. Glycocalyx thickness modul...

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Detalles Bibliográficos
Autores principales: Marhuenda, Emilie, Fabre, Christine, Zhang, Cunjie, Martin-Fernandez, Martà, Iskratsch, Thomas, Saleh, Ali, Bauchet, Luc, Cambedouzou, Julien, Hugnot, Jean-Philippe, Duffau, Hugues, Dennis, James W., Cornu, David, Bakalara, Norbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067292/
https://www.ncbi.nlm.nih.gov/pubmed/33894774
http://dx.doi.org/10.1186/s13046-021-01925-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067292/
https://www.ncbi.nlm.nih.gov/pubmed/33894774
http://dx.doi.org/10.1186/s13046-021-01925-7

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