Reduced Thiamine Availability and Hyperglycemia Impair Thiamine Transport in Renal Glomerular Cells through Modulation of Thiamine Transporter 2

Thiamine helps transketolase in removing toxic metabolites, counteracting high glucose-induced damage in microvascular cells, and progression of diabetic retinopathy/nephropathy in diabetic animals. Diabetic subjects show reduced thiamine levels. Hyperglycemia and reduced thiamine availability concu...

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Detalles Bibliográficos
Autores principales: Mazzeo, Aurora, Barutta, Federica, Bellucci, Linda, Trento, Marina, Gruden, Gabriella, Porta, Massimo, Beltramo, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067431/
https://www.ncbi.nlm.nih.gov/pubmed/33916491
http://dx.doi.org/10.3390/biomedicines9040385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067431/
https://www.ncbi.nlm.nih.gov/pubmed/33916491
http://dx.doi.org/10.3390/biomedicines9040385

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