The Role of the Rare Variants in the Genes Encoding the Alpha-Ketoglutarate Dehydrogenase in Alzheimer’s Disease

There is increasing evidence that several mitochondrial abnormalities are present in the brains of patients with Alzheimer’s disease (AD). Decreased alpha-ketoglutarate dehydrogenase complex (αKGDHc) activity was identified in some patients with AD. The αKGDHc is a key enzyme in the Krebs cycle. Thi...

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Detalles Bibliográficos
Autores principales: Csaban, Dora, Pentelenyi, Klara, Toth-Bencsik, Renata, Illes, Anett, Grosz, Zoltan, Gezsi, Andras, Molnar, Maria Judit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067443/
https://www.ncbi.nlm.nih.gov/pubmed/33917565
http://dx.doi.org/10.3390/life11040321

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067443/
https://www.ncbi.nlm.nih.gov/pubmed/33917565
http://dx.doi.org/10.3390/life11040321

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