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The Role of the Rare Variants in the Genes Encoding the Alpha-Ketoglutarate Dehydrogenase in Alzheimer’s Disease

There is increasing evidence that several mitochondrial abnormalities are present in the brains of patients with Alzheimer’s disease (AD). Decreased alpha-ketoglutarate dehydrogenase complex (αKGDHc) activity was identified in some patients with AD. The αKGDHc is a key enzyme in the Krebs cycle. Thi...

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Detalles Bibliográficos
Autores principales:	Csaban, Dora, Pentelenyi, Klara, Toth-Bencsik, Renata, Illes, Anett, Grosz, Zoltan, Gezsi, Andras, Molnar, Maria Judit
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067443/ https://www.ncbi.nlm.nih.gov/pubmed/33917565 http://dx.doi.org/10.3390/life11040321

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