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Concomitant Mutations G12D and G13D on the Exon 2 of the KRAS Gene: Two Cases of Women with Colon Adenocarcinoma

Colorectal cancer (CRC) is rapidly increasing representing the second most frequent cause of cancer-related deaths. From a clinical-molecular standpoint the therapeutically management of CRC focuses on main alterations found in the RAS family protein, where single mutations of KRAS are considered bo...

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Detalles Bibliográficos
Autores principales: De Falco, Elena, Pacini, Luca, Bastianelli, Daniela, Spinelli, Gian Paolo, Spoto, Chiara, Veltri, Enzo, Calogero, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067479/
https://www.ncbi.nlm.nih.gov/pubmed/33917572
http://dx.doi.org/10.3390/diagnostics11040659