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New Chloramphenicol Derivatives with a Modified Dichloroacetyl Tail as Potential Antimicrobial Agents

To combat the dangerously increasing pathogenic resistance to antibiotics, we developed new pharmacophores by chemically modifying a known antibiotic, which remains to this day the most familiar and productive way for novel antibiotic development. We used as a starting material the chloramphenicol b...

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Detalles Bibliográficos
Autores principales: Tsirogianni, Artemis, Kournoutou, Georgia G., Bougas, Anthony, Poulou-Sidiropoulou, Eleni, Dinos, George, Athanassopoulos, Constantinos M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067500/
https://www.ncbi.nlm.nih.gov/pubmed/33917453
http://dx.doi.org/10.3390/antibiotics10040394