Aryl Urea Based Scaffolds for Multitarget Drug Discovery in Anticancer Immunotherapies

Twenty-one styryl and phenethyl aryl ureas have been synthetized and biologically evaluated as multitarget inhibitors of Vascular endothelial growth factor receptor-2 VEGFR-2 and programmed death-ligand-1 (PD-L1) proteins in order to overcome resistance phenomena offered by cancer. The antiprolifera...

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Detalles Bibliográficos
Autores principales: Martín-Beltrán, Celia, Gil-Edo, Raquel, Hernández-Ribelles, Germán, Agut, Raül, Marí-Mezquita, Pilar, Carda, Miguel, Falomir, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067507/
https://www.ncbi.nlm.nih.gov/pubmed/33917617
http://dx.doi.org/10.3390/ph14040337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067507/
https://www.ncbi.nlm.nih.gov/pubmed/33917617
http://dx.doi.org/10.3390/ph14040337

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