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Absence of Cold-Inducible RNA-Binding Protein (CIRP) Promotes Angiogenesis and Regeneration of Ischemic Tissue by Inducing M2-Like Macrophage Polarization

Cold-inducible RNA-binding protein (CIRP) is an intracellular RNA-chaperone and extracellular promoter of inflammation, which is increasingly expressed and released under conditions of hypoxia and cold stress. The functional relevance of CIRP for angiogenesis and regeneration of ischemic muscle tiss...

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Detalles Bibliográficos
Autores principales: Kübler, Matthias, Beck, Sebastian, Fischer, Silvia, Götz, Philipp, Kumaraswami, Konda, Ishikawa-Ankerhold, Hellen, Lasch, Manuel, Deindl, Elisabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067566/
https://www.ncbi.nlm.nih.gov/pubmed/33916904
http://dx.doi.org/10.3390/biomedicines9040395