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Genotoxic Bystander Signals from Irradiated Human Mesenchymal Stromal Cells Mainly Localize in the 10–100 kDa Fraction of Conditioned Medium

Genotoxic bystander signals released from irradiated human mesenchymal stromal cells (MSC) may induce radiation-induced bystander effects (RIBEs) in human hematopoietic stem and progenitor cells (HSPC), potentially causing leukemic transformation. Although the source of bystander signals is evident,...

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Detalles Bibliográficos
Autores principales: Kohl, Vanessa, Fabarius, Alice, Drews, Oliver, Bierbaum, Miriam, Jawhar, Ahmed, Darwich, Ali, Weiss, Christel, Flach, Johanna, Brendel, Susanne, Kleiner, Helga, Seifarth, Wolfgang, Hofmann, Wolf-Karsten, Popp, Henning D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067571/
https://www.ncbi.nlm.nih.gov/pubmed/33916980
http://dx.doi.org/10.3390/cells10040827