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NRF2 Enables EGFR Signaling in Melanoma Cells

Receptor tyrosine kinases (RTK) are rarely mutated in cutaneous melanoma, but the expression and activation of several RTK family members are associated with a proinvasive phenotype and therapy resistance. Epidermal growth factor receptor (EGFR) is a member of the RTK family and is only expressed in...

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Detalles Bibliográficos
Autores principales: Kreß, Julia Katharina Charlotte, Jessen, Christina, Marquardt, André, Hufnagel, Anita, Meierjohann, Svenja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067606/
https://www.ncbi.nlm.nih.gov/pubmed/33916908
http://dx.doi.org/10.3390/ijms22083803