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Obeticholic Acid Derivative, T-2054 Suppresses Osteoarthritis via Inhibiting NF-κB-Signaling Pathway

Osteoarthritis (OA), a degenerative joint disorder, has been reported as the most common cause of disability worldwide. The production of inflammatory cytokines is the main factor in OA. Previous studies have been reported that obeticholic acid (OCA) and OCA derivatives inhibited the release of proi...

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Detalles Bibliográficos
Autores principales: Guo, Dandan, He, Liming, Gao, Yaoxin, Jin, Chenxu, Lin, Haizhen, Zhang, Li, Wang, Liting, Zhou, Ying, Yao, Jie, Duan, Yixin, Yang, Renzheng, Qiu, Wenwei, Jiang, Wenzheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067620/
https://www.ncbi.nlm.nih.gov/pubmed/33916928
http://dx.doi.org/10.3390/ijms22083807