hTERT-Driven Immortalization of RDEB Fibroblast and Keratinocyte Cell Lines Followed by Cre-Mediated Transgene Elimination

The recessive form of dystrophic epidermolysis bullosa (RDEB) is a crippling disease caused by impairments in the junctions of the dermis and the basement membrane of the epidermis. Using ectopic expression of hTERT/hTERT + BMI-1 in primary cells, we developed expansible cultures of RDEB fibroblasts...

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Detalles Bibliográficos
Autores principales: Evtushenko, Nadezhda A., Beilin, Arkadii K., Dashinimaev, Erdem B., Ziganshin, Rustam H., Kosykh, Anastasiya V., Perfilov, Maxim M., Rippa, Alexandra L., Alpeeva, Elena V., Vasiliev, Andrey V., Vorotelyak, Ekaterina A., Gurskaya, Nadya G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067634/
https://www.ncbi.nlm.nih.gov/pubmed/33916959
http://dx.doi.org/10.3390/ijms22083809

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067634/
https://www.ncbi.nlm.nih.gov/pubmed/33916959
http://dx.doi.org/10.3390/ijms22083809

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