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Rapamycin-Loaded Polymeric Nanoparticles as an Advanced Formulation for Macrophage Targeting in Atherosclerosis

Recently, rapamycin (Rapa) represents a potential drug treatment to induce regression of atherosclerotic plaques; however, its use requires site-specific accumulation in the vessels involved in the formation of the plaques to avoid the systemic effects resulting from its indiscriminate biodistributi...

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Detalles Bibliográficos
Autores principales: Craparo, Emanuela Fabiola, Cabibbo, Marta, Conigliaro, Alice, Barreca, Maria Magdalena, Musumeci, Teresa, Giammona, Gaetano, Cavallaro, Gennara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067637/
https://www.ncbi.nlm.nih.gov/pubmed/33916918
http://dx.doi.org/10.3390/pharmaceutics13040503