Active Transport of Hepatotoxic Pyrrolizidine Alkaloids in HepaRG Cells

1,2-unsaturated pyrrolizidine alkaloids (PAs) are secondary plant metabolites occurring as food contaminants that can cause severe liver damage upon metabolic activation in hepatocytes. However, it is yet unknown how these contaminants enter the cells. The role of hepatic transporters is only at the...

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Detalles Bibliográficos
Autores principales: Enge, Anne-Margarethe, Kaltner, Florian, Gottschalk, Christoph, Braeuning, Albert, Hessel-Pras, Stefanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067754/
https://www.ncbi.nlm.nih.gov/pubmed/33917053
http://dx.doi.org/10.3390/ijms22083821

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067754/
https://www.ncbi.nlm.nih.gov/pubmed/33917053
http://dx.doi.org/10.3390/ijms22083821

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