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Active Transport of Hepatotoxic Pyrrolizidine Alkaloids in HepaRG Cells
1,2-unsaturated pyrrolizidine alkaloids (PAs) are secondary plant metabolites occurring as food contaminants that can cause severe liver damage upon metabolic activation in hepatocytes. However, it is yet unknown how these contaminants enter the cells. The role of hepatic transporters is only at the...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067754/ https://www.ncbi.nlm.nih.gov/pubmed/33917053 http://dx.doi.org/10.3390/ijms22083821 |