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The OSMR Gene Is Involved in Hirschsprung Associated Enterocolitis Susceptibility through an Altered Downstream Signaling

Hirschsprung (HSCR) Associated Enterocolitis (HAEC) is a common life-threatening complication in HSCR. HAEC is suggested to be due to a loss of gut homeostasis caused by impairment of immune system, barrier defense, and microbiome, likely related to genetic causes. No gene has been claimed to contri...

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Detalles Bibliográficos
Autores principales: Bachetti, Tiziana, Rosamilia, Francesca, Bartolucci, Martina, Santamaria, Giuseppe, Mosconi, Manuela, Sartori, Serenella, De Filippo, Maria Rosaria, Di Duca, Marco, Obino, Valentina, Avanzini, Stefano, Mavilio, Domenico, Candiani, Simona, Petretto, Andrea, Pini Prato, Alessio, Ceccherini, Isabella, Lantieri, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067804/
https://www.ncbi.nlm.nih.gov/pubmed/33917126
http://dx.doi.org/10.3390/ijms22083831