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The OSMR Gene Is Involved in Hirschsprung Associated Enterocolitis Susceptibility through an Altered Downstream Signaling
Hirschsprung (HSCR) Associated Enterocolitis (HAEC) is a common life-threatening complication in HSCR. HAEC is suggested to be due to a loss of gut homeostasis caused by impairment of immune system, barrier defense, and microbiome, likely related to genetic causes. No gene has been claimed to contri...
Autores principales: | Bachetti, Tiziana, Rosamilia, Francesca, Bartolucci, Martina, Santamaria, Giuseppe, Mosconi, Manuela, Sartori, Serenella, De Filippo, Maria Rosaria, Di Duca, Marco, Obino, Valentina, Avanzini, Stefano, Mavilio, Domenico, Candiani, Simona, Petretto, Andrea, Pini Prato, Alessio, Ceccherini, Isabella, Lantieri, Francesca |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067804/ https://www.ncbi.nlm.nih.gov/pubmed/33917126 http://dx.doi.org/10.3390/ijms22083831 |
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