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Novel Pyrimidine Derivatives as Potential Anticancer Agents: Synthesis, Biological Evaluation and Molecular Docking Study

In the present paper, new pyrimidine derivatives were designed, synthesized and analyzed in terms of their anticancer properties. The tested compounds were evaluated in vitro for their antitumor activity. The cytotoxic effect on normal human dermal fibroblasts (NHDF) was also determined. According t...

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Detalles Bibliográficos
Autores principales: Tylińska, Beata, Wiatrak, Benita, Czyżnikowska, Żaneta, Cieśla-Niechwiadowicz, Aneta, Gębarowska, Elżbieta, Janicka-Kłos, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067809/
https://www.ncbi.nlm.nih.gov/pubmed/33917090
http://dx.doi.org/10.3390/ijms22083825