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A Consensus Model of Homology-Directed Repair Initiated by CRISPR/Cas Activity

The mechanism of action of ssODN-directed gene editing has been a topic of discussion within the field of CRISPR gene editing since its inception. Multiple comparable, but distinct, pathways have been discovered for DNA repair both with and without a repair template oligonucleotide. We have previous...

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Detalles Bibliográficos
Autores principales: Bloh, Kevin, Rivera-Torres, Natalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067812/
https://www.ncbi.nlm.nih.gov/pubmed/33917142
http://dx.doi.org/10.3390/ijms22083834