RGL2 Drives the Metastatic Progression of Colorectal Cancer via Preventing the Protein Degradation of β-Catenin and KRAS

SIMPLE SUMMARY: Aberrant activation of the Wnt/β-catenin pathway due to APC (adenomatous polyposis coli) loss and Kirsten ras (KRAS) mutation is highly associated with malignant evolution, e.g., metastasis, of colorectal cancer (CRC). Ral guanine nucleotide dissociation stimulator-like (RGL) protein...

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Detalles Bibliográficos
Autores principales: Sun, Meng-Shun, Yuan, Lan-Ting, Kuei, Chia-Hao, Lin, Hui-Yu, Chen, Yen-Lin, Chiu, Hui-Wen, Lin, Yuan-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067854/
https://www.ncbi.nlm.nih.gov/pubmed/33917100
http://dx.doi.org/10.3390/cancers13081763

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067854/
https://www.ncbi.nlm.nih.gov/pubmed/33917100
http://dx.doi.org/10.3390/cancers13081763

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