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BTLA/HVEM Axis Induces NK Cell Immunosuppression and Poor Outcome in Chronic Lymphocytic Leukemia

SIMPLE SUMMARY: Chronic lymphocytic leukemia (CLL) represents the most frequent B cell malignancy in Western countries and still remains as an incurable disease. Despite recent advances in targeted therapies including ibrutinib, idelalisib or venetoclax, resistance mechanisms have been described and...

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Detalles Bibliográficos
Autores principales: Sordo-Bahamonde, Christian, Lorenzo-Herrero, Seila, Gonzalez-Rodriguez, Ana P, R. Payer, Ángel, González-García, Esther, López-Soto, Alejandro, Gonzalez, Segundo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067870/
https://www.ncbi.nlm.nih.gov/pubmed/33917094
http://dx.doi.org/10.3390/cancers13081766