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Therapeutic Effect of Endothelin-Converting Enzyme Inhibitor on Chronic Kidney Disease through the Inhibition of Endoplasmic Reticulum Stress and the NLRP3 Inflammasome

Chronic inflammation and oxidative stress significantly contribute to the development and progression of chronic kidney disease (CKD). The NOD-like receptor family pyrin containing domain-3 (NLRP3) inflammasome plays a key role in the inflammatory response. The renal endothelin (ET) system is activa...

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Detalles Bibliográficos
Autores principales: Hsu, Yung-Ho, Zheng, Cai-Mei, Chou, Chu-Lin, Chen, Yi-Jie, Lee, Yu-Hsuan, Lin, Yuh-Feng, Chiu, Hui-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067871/
https://www.ncbi.nlm.nih.gov/pubmed/33917140
http://dx.doi.org/10.3390/biomedicines9040398