A Versatile Solid-Phase Approach to the Synthesis of Oligonucleotide Conjugates with Biodegradable Hydrazone Linker

One of the ways to efficiently deliver various drugs, including therapeutic nucleic acids, into the cells is conjugating them with different transport ligands via labile or stable bonds. A convenient solid-phase approach for the synthesis of 5′-conjugates of oligonucleotides with biodegradable pH-se...

Descripción completa

Detalles Bibliográficos
Autores principales: Meschaninova, Mariya I., Entelis, Nina S., Chernolovskaya, Elena L., Venyaminova, Alya G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067880/
https://www.ncbi.nlm.nih.gov/pubmed/33917095
http://dx.doi.org/10.3390/molecules26082119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067880/
https://www.ncbi.nlm.nih.gov/pubmed/33917095
http://dx.doi.org/10.3390/molecules26082119

Ejemplares similares