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A Versatile Solid-Phase Approach to the Synthesis of Oligonucleotide Conjugates with Biodegradable Hydrazone Linker
One of the ways to efficiently deliver various drugs, including therapeutic nucleic acids, into the cells is conjugating them with different transport ligands via labile or stable bonds. A convenient solid-phase approach for the synthesis of 5′-conjugates of oligonucleotides with biodegradable pH-se...
Autores principales: | Meschaninova, Mariya I., Entelis, Nina S., Chernolovskaya, Elena L., Venyaminova, Alya G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067880/ https://www.ncbi.nlm.nih.gov/pubmed/33917095 http://dx.doi.org/10.3390/molecules26082119 |
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