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Hypermethylation of dihydrofolate reductase promoter increases the risk of hypertension in Chinese

BACKGROUND: DNA methylation was considered to play an important role in hypertension. However, the direct association between dihydrofolate reductase (DHFR) promoter methylation and hypertension remains unclear. We thus aimed to investigate the relationship between DNA methylation of DHFR promoter a...

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Detalles Bibliográficos
Autores principales: Xu, Guodong, Wang, Zhiyi, Li, Lian, Li, Wenxia, Hu, Jingcen, Wang, Shuyu, Deng, Hongxia, Li, Bo, Wang, Changyi, Shen, Zhishen, Han, Liyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067893/
https://www.ncbi.nlm.nih.gov/pubmed/33912227
http://dx.doi.org/10.4103/jrms.JRMS_895_19