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Treatment Strategies for ARID1A-Deficient Ovarian Clear Cell Carcinoma

SIMPLE SUMMARY: Deleterious mutations in SWI/SNF chromatin remodeling genes, such as ARID1A, are present in more than 50% of cases of ovarian clear cell carcinoma (OCCC), a histological subtype of ovarian cancer prevalent in Asian countries. To efficiently treat OCCC, which is refractory to conventi...

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Detalles Bibliográficos
Autores principales: Takahashi, Kazuaki, Takenaka, Masataka, Okamoto, Aikou, Bowtell, David D. L., Kohno, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068058/
https://www.ncbi.nlm.nih.gov/pubmed/33917230
http://dx.doi.org/10.3390/cancers13081769