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Neurodegeneration Induced by Anti-IgLON5 Antibodies Studied in Induced Pluripotent Stem Cell-Derived Human Neurons

Anti-IgLON5 disease is a progressive neurological disorder associated with autoantibodies against a neuronal cell adhesion molecule, IgLON5. In human postmortem brain tissue, the neurodegeneration and accumulation of hyperphosphorylated tau (p-tau) are found. Whether IgLON5 antibodies induce neurode...

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Detalles Bibliográficos
Autores principales: Ryding, Matias, Gamre, Mattias, Nissen, Mette S., Nilsson, Anna C., Okarmus, Justyna, Poulsen, Anne A. E., Meyer, Morten, Blaabjerg, Morten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068068/
https://www.ncbi.nlm.nih.gov/pubmed/33917676
http://dx.doi.org/10.3390/cells10040837