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Dabrafenib Promotes Schwann Cell Differentiation by Inhibition of the MEK-ERK Pathway

Schwann cell differentiation involves a dynamic interaction of signaling cascades. However, much remains to be elucidated regarding the function of signaling molecules that differ depending on the context in which the molecules are engaged. Here, we identified a small molecule, dabrafenib, which pro...

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Detalles Bibliográficos
Autores principales: Park, Kyuhee, Shin, Yoonkyoung, Lee, Gyeongbeen, Park, Hwantae, Choi, Yongmun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068149/
https://www.ncbi.nlm.nih.gov/pubmed/33917810
http://dx.doi.org/10.3390/molecules26082141