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Novel Thiol Containing Hybrid Antioxidant-Nitric Oxide Donor Small Molecules for Treatment of Glaucoma

Oxidative stress induced death and dysregulation of trabecular meshwork (TM) cells contribute to the increased intraocular pressure (IOP) in primary open angle (POAG) glaucoma patients. POAG is one of the major causes of irreversible vision loss worldwide. Nitric oxide (NO), a small gas molecule, ha...

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Detalles Bibliográficos
Autores principales: Amankwa, Charles E., Gondi, Sudershan R., Dibas, Adnan, Weston, Courtney, Funk, Arlene, Nguyen, Tam, Nguyen, Kytai T., Ellis, Dorette Z., Acharya, Suchismita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068288/
https://www.ncbi.nlm.nih.gov/pubmed/33917924
http://dx.doi.org/10.3390/antiox10040575