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Mechanistic Fingerprinting Reveals Kinetic Signatures of Resistance to Daptomycin and Host Defense Peptides in Streptococcus mitis-oralis

Streptococcus mitis-oralis (S. mitis-oralis) infections are increasingly prevalent in specific populations, including neutropenic cancer and endocarditis patients. S. mitis-oralis strains have a propensity to evolve rapid, high-level and durable resistance to daptomycin (DAP-R) in vitro and in vivo,...

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Detalles Bibliográficos
Autores principales: Yeaman, Michael R., Chan, Liana C., Mishra, Nagendra N., Bayer, Arnold S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068394/
https://www.ncbi.nlm.nih.gov/pubmed/33918000
http://dx.doi.org/10.3390/antibiotics10040404