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Altered DNA repair creates novel Alu/Alu repeat‐mediated deletions
Alu elements are the most abundant source of nonallelic homology that influences genetic instability in the human genome. When there is a DNA double‐stranded break, the Alu element's high copy number, moderate length and distance and mismatch between elements uniquely influence recombination pr...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068675/ https://www.ncbi.nlm.nih.gov/pubmed/33675284 http://dx.doi.org/10.1002/humu.24193 |