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Simvastatin treatment varies the radiation response of human breast cells in 2D or 3D culture
Background Statins inhibit the cholesterol biosynthesis and are used as cholesterol-lowering agents in fat-metabolism disorders. Furthermore, several studies state that statins have supportive functions in breast cancer treatment. Therefore, simvastatin (SVA) as a potential radiosensitizer should be...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068713/ https://www.ncbi.nlm.nih.gov/pubmed/33313978 http://dx.doi.org/10.1007/s10637-020-01046-6 |