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Simvastatin treatment varies the radiation response of human breast cells in 2D or 3D culture

Background Statins inhibit the cholesterol biosynthesis and are used as cholesterol-lowering agents in fat-metabolism disorders. Furthermore, several studies state that statins have supportive functions in breast cancer treatment. Therefore, simvastatin (SVA) as a potential radiosensitizer should be...

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Detalles Bibliográficos
Autores principales:	Manda, Katrin, Juerß, Dajana, Fischer, Paul, Schröder, Annemarie, Koenen, Annelie, Hildebrandt, Guido
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2020
Materias:	Preclinical Studies
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068713/ https://www.ncbi.nlm.nih.gov/pubmed/33313978 http://dx.doi.org/10.1007/s10637-020-01046-6

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