Novel Benzenesulfonate Scaffolds with a High Anticancer Activity and G2/M Cell Cycle Arrest

SIMPLE SUMMARY: Sulfonate derivatives have limited application in pharmacology. Only few examples of small-molecule alkylating agents used as DNA poisons are known. This is the first report presenting strong anticancer activity of aromatic sulfonates based on quinazolines. The screening revealed tha...

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Detalles Bibliográficos
Autores principales: Malarz, Katarzyna, Mularski, Jacek, Kuczak, Michał, Mrozek-Wilczkiewicz, Anna, Musiol, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068801/
https://www.ncbi.nlm.nih.gov/pubmed/33918637
http://dx.doi.org/10.3390/cancers13081790

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068801/
https://www.ncbi.nlm.nih.gov/pubmed/33918637
http://dx.doi.org/10.3390/cancers13081790

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