The F-Actin-Binding MPRIP Forms Phase-Separated Condensates and Associates with PI(4,5)P2 and Active RNA Polymerase II in the Cell Nucleus

Here, we provide evidence for the presence of Myosin phosphatase rho-interacting protein (MPRIP), an F-actin-binding protein, in the cell nucleus. The MPRIP protein binds to Phosphatidylinositol 4,5-bisphosphate (PIP2) and localizes to the nuclear speckles and nuclear lipid islets which are known to...

Descripción completa

Detalles Bibliográficos
Autores principales: Balaban, Can, Sztacho, Martin, Blažíková, Michaela, Hozák, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068864/
https://www.ncbi.nlm.nih.gov/pubmed/33918018
http://dx.doi.org/10.3390/cells10040848

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068864/
https://www.ncbi.nlm.nih.gov/pubmed/33918018
http://dx.doi.org/10.3390/cells10040848

Ejemplares similares