hTERT Downregulation Attenuates Resistance to DOX, Impairs FAK-Mediated Adhesion, and Leads to Autophagy Induction in Breast Cancer Cells

Telomerase is known to contribute to telomere maintenance and to provide cancer cell immortality. However, numerous reports are showing that the function of the enzyme goes far beyond chromosome ends. The study aimed to explore how telomerase downregulation in MCF7 and MDA-MB-231 breast cancer cells...

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Detalles Bibliográficos
Autores principales: Romaniuk-Drapała, Aleksandra, Totoń, Ewa, Konieczna, Natalia, Machnik, Marta, Barczak, Wojciech, Kowal, Dagmar, Kopczyński, Przemysław, Kaczmarek, Mariusz, Rubiś, Błażej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068966/
https://www.ncbi.nlm.nih.gov/pubmed/33920284
http://dx.doi.org/10.3390/cells10040867

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068966/
https://www.ncbi.nlm.nih.gov/pubmed/33920284
http://dx.doi.org/10.3390/cells10040867

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