Cargando…

In Silico Prediction of Drug–Drug Interactions Mediated by Cytochrome P450 Isoforms

Drug–drug interactions (DDIs) can cause drug toxicities, reduced pharmacological effects, and adverse drug reactions. Studies aiming to determine the possible DDIs for an investigational drug are part of the drug discovery and development process and include an assessment of the DDIs potential media...

Descripción completa

Detalles Bibliográficos
Autores principales: Dmitriev, Alexander V., Rudik, Anastassia V., Karasev, Dmitry A., Pogodin, Pavel V., Lagunin, Alexey A., Filimonov, Dmitry A., Poroikov, Vladimir V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068971/
https://www.ncbi.nlm.nih.gov/pubmed/33924315
http://dx.doi.org/10.3390/pharmaceutics13040538