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In Silico Prediction of Drug–Drug Interactions Mediated by Cytochrome P450 Isoforms
Drug–drug interactions (DDIs) can cause drug toxicities, reduced pharmacological effects, and adverse drug reactions. Studies aiming to determine the possible DDIs for an investigational drug are part of the drug discovery and development process and include an assessment of the DDIs potential media...
Autores principales: | Dmitriev, Alexander V., Rudik, Anastassia V., Karasev, Dmitry A., Pogodin, Pavel V., Lagunin, Alexey A., Filimonov, Dmitry A., Poroikov, Vladimir V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068971/ https://www.ncbi.nlm.nih.gov/pubmed/33924315 http://dx.doi.org/10.3390/pharmaceutics13040538 |
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