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Synthesis of Polyanionic C5-Modified 2′-Deoxyuridine and 2′-Deoxycytidine-5′-Triphosphates and Their Properties as Substrates for DNA Polymerases

Modified 2′-deoxyribonucleotide triphosphates (dNTPs) have widespread applications in both existing and emerging biomolecular technologies. For such applications it is an essential requirement that the modified dNTPs be substrates for DNA polymerases. To date very few examples of C5-modified dNTPs b...

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Detalles Bibliográficos
Autores principales: Dutson, Claire, Allen, Esther, Thompson, Mark J., Hedley, Joseph H., Murton, Heather E., Williams, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069024/
https://www.ncbi.nlm.nih.gov/pubmed/33924626
http://dx.doi.org/10.3390/molecules26082250