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Synthesis of Polyanionic C5-Modified 2′-Deoxyuridine and 2′-Deoxycytidine-5′-Triphosphates and Their Properties as Substrates for DNA Polymerases
Modified 2′-deoxyribonucleotide triphosphates (dNTPs) have widespread applications in both existing and emerging biomolecular technologies. For such applications it is an essential requirement that the modified dNTPs be substrates for DNA polymerases. To date very few examples of C5-modified dNTPs b...
Autores principales: | Dutson, Claire, Allen, Esther, Thompson, Mark J., Hedley, Joseph H., Murton, Heather E., Williams, David M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069024/ https://www.ncbi.nlm.nih.gov/pubmed/33924626 http://dx.doi.org/10.3390/molecules26082250 |
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