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The Leloir Cycle in Glioblastoma: Galactose Scavenging and Metabolic Remodeling

SIMPLE SUMMARY: Proliferation of glioblastoma (GBM) depends on access to extracellular nutrients. Inadequate tumor perfusion creates a short supply of the most common nutrients, such as glucose (Glc) and glutamine. As a result, GBMs undergo metabolic remodeling and scavenge alternative nutrients fro...

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Detalles Bibliográficos
Autores principales: Sharpe, Martyn A., Ijare, Omkar B., Baskin, David S., Baskin, Alexandra M., Baskin, Brianna N., Pichumani, Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069026/
https://www.ncbi.nlm.nih.gov/pubmed/33920278
http://dx.doi.org/10.3390/cancers13081815