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Depleting Tumor Cells Expressing Immune Checkpoint Ligands—A New Approach to Combat Cancer

Antibodies against inhibitory immune checkpoint molecules (ICPMs), referred to as immune checkpoint inhibitors (ICIs), have gained a prominent place in cancer therapy. Several ICIs in clinical use have been engineered to be devoid of effector functions because of the fear that ICIs with preserved ef...

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Detalles Bibliográficos
Autores principales: Marcucci, Fabrizio, Rumio, Cristiano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069236/
https://www.ncbi.nlm.nih.gov/pubmed/33921301
http://dx.doi.org/10.3390/cells10040872