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A Role for RAGE in DNA Double Strand Breaks (DSBs) Detected in Pathological Placentas and Trophoblast Cells

Impaired DNA damage responses are associated with several diseases, including pregnancy complications. Recent research identified an ATM-kinase dependent function for the nuclear isoform of the receptor for advanced glycation end-products (RAGE) during double strand break (DSB)-repair. RAGE contribu...

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Detalles Bibliográficos
Autores principales: Tsai, Kary Y.F., Tullis, Benton, Breithaupt, Katrina L., Fowers, Rylan, Jones, Nelson, Grajeda, Samuel, Reynolds, Paul R., Arroyo, Juan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069300/
https://www.ncbi.nlm.nih.gov/pubmed/33918759
http://dx.doi.org/10.3390/cells10040857