Cargando…

Synthesis and Evaluation of Novel 2,2-Dimethylthiochromanones as Anti-Leishmanial Agents

Within this work, we describe the design and synthesis of a range of novel thiochromanones based on natural products reported to possess anti-leishmanial action, and their synthetic derivatives. All compounds were elaborated via the key intermediate 2,2,6-trimethoxythiochromanone, which was modified...

Descripción completa

Detalles Bibliográficos
Autores principales: Coll, Seán, Alhazmi, Mohammad, de Aguiar Amaral, Patrícia, Bourgeade-Delmas, Sandra, Le Lamer, Anne-Cécile, Barlow, James W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8069510/
https://www.ncbi.nlm.nih.gov/pubmed/33921252
http://dx.doi.org/10.3390/molecules26082209